BEIR VII develops the most up-to-date and comprehensive risk estimates for cancer and other health effects from exposure to low-level ionizing radiation. It is among the first reports of its kind to include detailed estimates for cancer incidence in addition to cancer mortality. In general, BEIR VII supports previously reported risk estimates for cancer and leukemia, but the availability of new and more extensive data have strengthened confidence in these estimates. A comprehensive review of available biological and biophysical data supports a "linear-no-threshold" (LNT) risk model?that the risk of cancer proceeds in a linear fashion at lower doses without a threshold and that the smallest dose has the potential to cause a small increase in risk to humans. The report is from the Board on Radiation Research Effects that is now part of the newly formed Nuclear and Radiation Studies Board.


Table of Contents


Front Matter
Public Summary & Executive Summary
1 Background Information
2 Molecular and Cellular Responses to Ionizing Radiation
3 Radiation-Induced Cancer: Mechanisms, Quantitative Experimental
Studies and the Role of Genetic Factors
4 Heritable Genetic Effects of Radiation in Human Populations
5 Background for Epidemiologic Methods
6 Atomic Bomb Survivor Studies
7 Medical Radiation Studies
8 Occupational Radiation Studies
9 Environmental Radiation Studies
10 Integration of Biology and Epidemiology
11 Risk Assessment Models and Methods
12 Estimating Cancer Risk
13 Summary and Research Needs
Appendix A: Basic Biological and Genetic Concepts
Appendix B: Commetary on "Radiation from Medical Procedures in the
Pathogenesis of Cancer and Ischemic Heart Disease: Dose-Response
Studies with Physicians per 100,000 Populations"
Appendix C: Issues Raised by the Institute for Energy and
Environment Research (IEER)
Appendix D: Hormesis
Appendix E: Fifteen-Country Workers Study
References
Glossary
Committee Biographies
Index