The building of the Panama Canal was one of the greatest engineering feats in human history. A tale of exploration, conquest, money, politics, and medicine, PANAMA FEVER charts the challenges that marked the long, labyrinthine road to the building of the canal. Drawing on a wealth of new materials and sources, Matthew Parker brings to life the men (including Benjamin Franklin, Thomas Jefferson, and Ulysses S Grant) who recognized the impact a canal would have on global politics and economics, and adds new depth to the familiar story of Teddy Roosevelt's remarkable triumph in making the waterway a reality. Parker's grim chronicle of the actual construction lends another meaning to Panama fever. As thousands of workers succumbed to dysentery, yellow fever, and malaria, scientists raced to stop the deadly epidemics so that work could continue. The treatments they developed changed the course of medical history. The opening of the Panama Canal in 1914 spelled the end of the Victorian Age and the beginning of the American Century. PANAMA FEVER brilliantly captures the innovative thinking and backbreaking labor, as well as the commercial and political interests, that helped make America a global power.