Introduction.- Part I The Changing CBRN Risk Landscape.- The XXI Century: The Epoch of Advanced Military Systems and Growing Vulnerabilities.- The Dark Side of Nuclear Energy: Risks of Proliferation from Domestic Fuel Cycle Technologies.- Chemical and Biological Risks in the 21st Century.- Neuroscience-Based Weapons.- Hybrid Emerging Threats and AI Information Warfare: The Story of the Cyber-AI Deception Machine.- Artificial Intelligence and Warfare.- Artificial Intelligence in Autonomous Weapon Systems.- Understanding the Threat Posed by COTS and Small UAVs Armed with CBW.- Education and Training as a Disruptive Dual Use Technology.- Part II Evolving Risk Mitigation Strategies and Technologies.- Detection and Identification Technologies for CBRN Agents.- Chemical Forensics.- Recent Developments in Clinical Toxicology and the Use of Weaponized Nerve Agents.- Diagnosing the Cause of Disease - Interactive Teaching Approaches.- Evaluation Systems for Biological Security Risk Mitigation Training and Education.- Biological Forensics.