A Golden Retriever & His Two Dads tells the story of how Dan's Golden Retriever, Willy, helps him to find a life partner. Willy has been the love of Dan's life for over nine years helping him survive a life-threatening disease. But now Dan would like a relationship with someone of his own species. One morning at the local coffee shop, Willy pesters a handsome patron to the point that Dan must intervene and apologize. His name is James and he's a movie producer. A romance develops but long distance relationships are difficult to maintain.

Willy's ears perk up when he hears James announce that he is leaving for six weeks to make a film on Cape Cod. He invites Dan and Willy to join him and even offers to hire them to work on the film crew. Now Dan and Willy must decide if they are ready to commit to living and working with James. They accept the offer and thus the experiment on Cape Cod begins.

It is uncanny when they discover that the drama of the movie seems to mirror the adventure that Willy, Dan & James are about to embark on. Dan is nervous about living with James as they are temperamental opposites. Starting a new relationship while making a film provides them with ample obstacles to resolve their different approaches; especially when Willy suddenly collapses with a mysterious sickness or when Dan's parents show up on the set uninvited, to name a few.