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Cell-wide Metabolic Alterations Associated with Malignancy: Volume 543

Cell-wide Metabolic Alterations Associated with Malignancy: Volume 543

Hardback
Publication Date: 15/06/2014
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This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods providing a a theoretical overview on metabolic alterations of cancer cells and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo. Malignant cells exhibit metabolic changes when compared to their normal counterparts, owing to both genetic and epigenetic alterations. Although such a metabolic rewiring has recently been indicated as "yet another" general hallmark of cancer, accumulating evidence suggests that the metabolic alterations of each neoplasm rather represent a molecular signature that intimately accompanies, and hence cannot be severed from, all facets of malignant transformation.
ISBN:
9780128013298
9780128013298
Category:
Medical genetics
Format:
Hardback
Publication Date:
15-06-2014
Language:
English
Publisher:
Elsevier Science Publishing Co Inc
Country of origin:
United States
Pages:
384
Dimensions (mm):
229x152x0mm
Weight:
0.84kg

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