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Factors Influencing Mammalian Kidney Development: Implications for Health in Adult Life

Factors Influencing Mammalian Kidney Development: Implications for Health in Adult Life

Implications for Health in Adult Life

by John F. BertramM. Jane Black Georgina Caruana and others
Paperback
Publication Date: 10/06/2008

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In this monograph the authors have emphasized a number of important concepts in mammalian kidney development. Emphasis has been put on methodology so that the reader can understand how certain results or conclusions were reached and what the optimal methods for reliable results to be obtained are. In addition, as well as descriptions of the morphology there is information on the genetic basis of the structural development. In addition much attention has been paid to how nephron number may be altered by changes in the environment of the developing kidney and to the consequences for the remaining nephron gene expression and kidney function when total nephron number is altered. The consequences for the health of the adult, upon the formation of an adult kidney with altered nephron number and (potentially) gene expression, can be quite serious. The epigenetic mechanisms by which such changes can occur are introduced as a very fertile field for future investigation.
ISBN:
9783540777670
9783540777670
Category:
Animal physiology
Format:
Paperback
Publication Date:
10-06-2008
Language:
English
Publisher:
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Country of origin:
Germany
Pages:
79
Dimensions (mm):
235x155x5mm
Weight:
0.16kg

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