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Formulating Poorly Water Soluble Drugs

Formulating Poorly Water Soluble Drugs

by Alan B. WattsDave A. Miller and Robert O. Williams III
Hardback
Publication Date: 16/11/2016
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The objective of this volume is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist's approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound's physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at minimum a working knowledge of each of the abovementioned facets and detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop
ISBN:
9783319426075
9783319426075
Category:
Pharmaceutical technology
Format:
Hardback
Publication Date:
16-11-2016
Publisher:
Springer International Publishing AG
Country of origin:
Switzerland
Edition:
2nd Edition
Pages:
779
Dimensions (mm):
235x155x43mm
Weight:
1.72kg

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