Galectins

Galectins

by Anatole A. KlyosovDavid Platt and Zbigniew J. Witczak

Hardback Publication Date: 26/06/2008

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The comprehensive guide to the current understanding of galectins
and their promising potential in drug design



This is the first book focusing on galectins. It was inspired by
topics discussed at the symposium "Galectins: Structures,
Functions, and Therapeutic Targets" that was a part of the 234th
American Chemical Society meeting in 2007. To help chemists,
biochemists, and others understand the challenges inherent in the
study of galectins and build on recent advances in the field, the
editors have compiled articles from leading experts on galectins
and their biomedical applications. Galectins includes:

* An overview of early galectin research

* An explanation of the nature of galectins

* A discussion of the structure and functions of galectins, their
ligand specificity and molecular mechanisms of action, and the
localization of galectins in the cell

* An exploration of the roles galectins play in tumor growth and
cancer, fibrosis, inflammation, and immunity

* A discussion of the effect of galectins on cell migration,
angiogenesis, and chemoresistance

* An introduction to new approaches to designing galectin
inhibitors



This is the premier reference on galectins for organic, medicinal,
carbohydrate, and pharmaceutical chemists, biochemists, molecular
and cell biologists, pharmacologists, cancer researchers, and
graduate-level students in these disciplines, as well as clinicians
and drug developers.
ISBN:
9780470373187
9780470373187
Category:
Biochemistry
Format:
Hardback
Publication Date:
26-06-2008
Language:
English
Publisher:
John Wiley & Sons Inc
Country of origin:
United States
Pages:
280
Dimensions (mm):
240x160x24mm
Weight:
0.64kg

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