Free Shipping on Order Over $60
AfterPay Available
Handbook of Psychopharmacology

Handbook of Psychopharmacology

Volume 10: Neoroleptics and Schizophrenia

by Leslie Iversen
Publication Date: 12/10/2011
or 4 easy payments of $51.04 with
This item qualifies for FREE delivery
Perhaps more than any other group of psychotropic drugs, the neuroleptics are a focus for integrating clinical application, neurotransmitter disposition, and pathophysiologic mechanisms of mental illness. Neuroleptic is a term referring to drugs of several chemical classes-phenothiazines, thioxan- thenes, and butyrophenones-which have in common a selective ability to alleviate schizophrenic symptoms. Delay and Deniker derived the word neuroleptic from the Greek meaning "to grasp the neuron. " They coined the name because they noted that therapeutic responses to chlorpromazine tended to accompany the onset of neurological, extrapyramidal side effects, which they therefore felt related to the essence of the drug's antischizo- phrenic actions. Subsequent research, particularly relating to neuroleptic effects on dopamine receptors, suggests that both therapeutic and neurologic untoward effects involve dopaminergic mechanisms, explaining their close though not invariant association. The chapter by Davis and Garver summa- rizes clinical facets of neuroleptics, analyzing their apparently specific clinical effects as well as reviewing practical features of drug use.
Crane's chapter deals with tardive dyskinesia and other neurological side effects. Fielding and Lal discuss behavioral studies in animals which provide models for assessing the drugs' therapeutic efficacy. Janssen and Van Bever deal with the remarkable structure-activity relationships of the butyrophenones, the most potent and selective neuroleptics which were almost single-handedly devel- oped through the brilliant efforts of Paul Janssen. Shore and Giachetti describe basic and clinical features of reserpine, the neurotransmitter effects of which differ from .
Publication Date:
Springer-Verlag New York Inc.
Country of origin:
United States
Dimensions (mm):

This title is in stock with our Australian supplier and arrives at our Sydney warehouse within 10-15 working days of you placing an order.

Once received into our warehouse we will despatch it to you with a Shipping Notification which includes online tracking.

Please check the estimated delivery times below for your region, for after your order is despatched from our warehouse:

ACT Metro  2 working days

NSW Metro  2 working days

NSW Rural  2 - 3 working days

NSW Remote  2 - 5 working days

NT Metro  3 - 6 working days

NT Remote  4 - 10 working days

QLD Metro  2 - 4 working days

QLD Rural  2 - 5 working days

QLD Remote  2 - 7 working days

SA Metro  2 - 5 working days

SA Rural  3 - 6 working days

SA Remote  3 - 7 working days

TAS Metro  3 - 6 working days

TAS Rural  3 - 6 working days

VIC Metro  2 - 3 working days

VIC Rural  2 - 4 working days

VIC Remote  2 - 5 working days

WA Metro  3 - 6 working days

WA Rural  4 - 8 working days

WA Remote  4 - 12 working days

Customer Reviews

Be the first to review Handbook of Psychopharmacology.