Long suspected of guilt in his daughter Madeline's disappearance, Branson Turaco takes an abrupt turn in his life when a lock of Madeline's hair is found in a child predator's home. Branson buys an unlicensed handgun, enlists the help of a disgraced filmmaker and a desperate intern, and heads out onto the open road.

Clinging to the dim hope that his daughter might still be alive, Branson finds himself pursued by a team of post-human assassins with glowing skin and a symbiotic relationship with a mysterious species of eel. Lost in a psychedelic world of uncontrollable substances and bizarre evolutions, he must decide how much he is willing to sacrifice in order to unravel the mystery of Madeline's disappearance.

What remains of a man once he sheds his humanity in the name of vengeance?