Isreal (Izzy) and his sister Julia (JuJu) are 3 year old twins who live with their mommy and daddy in the Southward of the great city of Newark, New Jersey. They love going on various adventures around the house, throughout the city, surrounding states and countries. On one such adventure Izzy and JuJu discovered that they have special powers. They can talk to living things! JuJu can talk with animals, while Izzy talks to insects. This leads to a very interesting life for these two.