Zoe Morgan was just ten years old when her life changed forever. Her sister, Rose, died of a rare illness, her parents turned into people she didn't know, and Zoe's lonely childhood drove her to excel in her studies.

As a graduate of Yale, Zoe takes a leave of absence from medical school to work in a shelter for abused children in New York, where she meets well-known child advocacy attorney, Austin Roberts.  Austin is bowled over by her beauty, brains and talent. He is her first love and the man she marries.

Austin and Zoe have a perfect life and, after the birth of their longed-for daughter Jaime, Zoe knows that the aching void she had lived through for twenty-four years is finally complete. But it is only then that the true impact of Rose's death all those years ago affects their lives in a way that nobody could ever have imagined.