The FF are pulled into a madman's scheme when those closest to them are drawn back through time as a lure to get the foursome to follow. And what awaits them in the year 1483 is a man with a quest to transform the world - literally. Meet the alchemist supreme: Ultimate Diablo! And his plans for the Fantastic Four aren't pretty. Plus: something strange has happened at Nursery Two, the Baxter Building's Think Tank counterpart in Oregon. It's disappeared, seemingly swallowed up by the earth itself! And if you think that heralds the return of the macabre Mole Man, go to the head of the class! This book collects "Ultimate Fantastic Four" Nos. 39-41 and "Annual" No. 2.