The Last Man is a post-apocalyptic science fiction novel by Mary Shelley, which was first published in 1826. The book tells of a future world that has been ravaged by a plague. The novel was harshly reviewed at the time, and was virtually unknown – having been eclipsed by Shelley's more popular works – until a scholarly revival in the 1960s. It contains semi-biographical portraits of Romantic figures in Shelley's circle, particularly Shelley's late husband Percy Bysshe Shelley and Lord Byron. Plot Summary: Introduction Mary Shelley states in the introduction that in 1818 she discovered, in the Sibyl's cave near Naples, a collection of prophetic writings painted on leaves by the Cumaean Sibyl. She has edited these writings into the current narrative, the first-person narrative of a man living at the end of the 21st century, commencing in 2073 and concluding in 2100. Despite the chronological setting, the world of The Last Man appears to be relatively similar to the era in which it was written. Failure of Romantic Political Ideals The Last Man not only laments the loss of Shelley's friends, but also questions the Romantic political ideals for which they stood. In a sense, the plague is metaphorical, since the revolutionary idyll of the élite group is corroded from within by flaws of human nature. As literary scholar Kari Lokke writes, "in its refusal to place humanity at the center of the universe, its questioning of our privileged position in relation to nature, then, The Last Man constitutes a profound and prophetic challenge to Western humanism." Specifically, Mary Shelley, in making references to the failure of the French Revolution and the Godwinian, Wollstonecraftian, and Burkean responses to it, "attacks Enlightenment faith in the inevitability of progress through collective efforts". Isolation Hugh Luke argues, "By ending her story with the picture of the Earth's solitary inhabitant, she has brought nearly the whole weight of the novel to bear upon the idea that the condition of the individual being is essentially isolated and therefore ultimately tragic". Shelley shares this theme of tragic isolation with the poetry of Lord Byron and William Wordsworth. Science and Medicine Just as her earlier and better known novel Frankenstein (1818) engaged with scientific questions of electromagnetism, chemistry, and materialism, The Last Man finds Shelley again attempting to understand the scope of scientific inquiry. Unlike the earlier novel's warnings about Faustian over-reaching, this novel's devastating apocalypse strongly suggests that medicine had become too timid and ultimately come too late.