Follow Nathan Gardner (Nicolas Cage), Theresa Gardner (Joely Richardson) and their three children, whose recent retreat to rural life quickly crumbles when a meteorite crashes into their front yard.

The mysterious aerolite seems to melt into the earth, infecting both the land and the properties of space-time. Mutant forms of technicolour flora start sprouting, while local animals begin to display bizarre deformities. Soon, the Gardners realise that they too are susceptible to the extra-terrestrial pathogen and must escape the contagious cloud that has consumed their farm. With the help of a friendly hydrologist (Elliot Knight) and eccentric neighbour (Tommy Chong), the family attempts to battle a nebulous entity that they can barely begin to understand. What chance can a few humans have against a force capable of traversing the gulf between worlds, a nightmarish being that exists beyond the limits of the human spectrum?