Les (Matthew Broderick) and Nat (Alice Eve) both have secrets. On a business trip to Chicago, their plane is diverted by fog and they find themselves stranded in Albuquerque. Anxious and irritable, Les is drawn back into the city by a past experience that has haunted him. Natalie, refusing to leave his side, follows along as her own secrets are slowly revealed.

This unlikely pair is about to discover more about each other than they ever thought possible. As their rapport grows, they search out excitement in this most unlikely of locales. It is one crazy layover and one dirty weekend.