Set six, eight or twelve years after the Civil War, a stagecoach hurtles through the wintry Wyoming landscape. The passengers, bounty hunter John Ruth (Kurt Russell) and his fugitive Daisy Domergue (Jennifer Jason Leigh), race towards the town of Red Rock where Ruth--known in these parts as "The Hangman--will bring Domergue to justice. Along the road, they encounter two strangers: Major Marquis Warren (Samuel L. Jackson), a black former union soldier turned infamous bounty hunter; and Chris Mannix (Walton Goggins), a southern renegade who claims to be the town's new Sheriff. Losing their way in the blizzard, Ruth, Domergue, Warren and Mannix seek refuge at 'Minnie's Haberdashery', a stagecoach stopover on a lonely mountain pass. Here they are greeted not by the proprietor but by four unfamiliar faces. Bob (Demian Bichir), who's taking care of Minnie's while she's visiting her mother, is holed up with the hangman of Red Rock, Oswaldo Mobray (Tim Roth), cow-puncher Joe Gage (Michael Madsen) and Confederate General Sanford Smithers (Bruce Dern).

As the storm engulfs the mountainside stopover, our eight travellers come to learn they may not make it to Red Rock after all...