When hedge fund tycoon Neil (Danny Masterson) treats his friends to an island getaway, they are assured the time of their lives. Just when they thought the weekend couldn't get any better, a mysterious figure known as The Man (Pierce Brosnan), introduces them to a drug called 'Urge' that propels them into a state of unbridled euphoria. While Urge feels like the perfect drug, it comes with a catch: it can only be taken once and only once--but experimentation, becomes obsession. People throughout the island find themselves unable to resist using Urge again and again, leading them to suffer the drug's sole side effect: the complete inability to control their urges. The island quickly devolves into chaos as people succumb to their violent, sexual and animalistic impulses. Jason, the wayward libertine of the group and the only one to be unaffected by the drug, is left to assume the role of their saviour. What Jason finds, however, is that Urge is much more than a drug and may lead to the end of civilisation.