"International Review of Cytology" presents current advances and comprehensive reviews in cell biology, both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Articles in this volume address the pathophysiological dynamics of human ovarian surface epithelial cells in epithelial ovarian carcinogenesis; morphodynamics of the secretory pathway; aspects of collagen mineralization in hard tissue frmation; the hypoxia-inducible factor and tumor progression along the angiogenic pathway; multidrug resistance in yeast candida; intracellular coupling of interstitial cells of cajal in the digestive tract; and chromatin organization in the mammalian nucleus.