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On Rheostasis

On Rheostasis

The Hierarchical Organization of Physiological Stability

by Tyler John Stevenson
Hardback
Publication Date: 21/03/2024

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One of the fundamental concepts in life sciences, and medical and veterinary practice is that our internal states maintain stability through a process called Homeostasis. Originally coined by Walter B. Cannon, homeostasis describes a series of internal physiological components that seek to maintain a fixed state established by set points (e.g., 98°F core body temperature). Any deviations in homeostasis leads to severe pathology such as hypothermia or death. But it is becoming increasingly clear that homeostatic set points vary predictably with time or new, temporary set points can be created. In this book, the concept of rheostasis is re-examined through the lens of 30 years of discoveries that include newly identified genes, increases in our understanding of the internal activity in cells, scientific advances in how neurons in the brain communicate with each other, complex imaging, and identifying how the brain creates representations of our environment. On Rheostasis aims to present a new way of thinking about how our bodies maintain physiological stability and proposes that homeostasis and rheostasis act independently and evolved separately to maintain stability by entirely distinct processes. The new conceptual model described indicates that our physiological systems have a tiered level of organization with significant implications for how we maintain our health and the treatment of common illnesses such as some bacterial or viral infections, to complex treatments for psychiatric and neurological disorders.
ISBN:
9780197665572
9780197665572
Category:
History of science
Format:
Hardback
Publication Date:
21-03-2024
Language:
English
Publisher:
Oxford University Press, Incorporated
Country of origin:
United States
Dimensions (mm):
229x163x25.4mm
Weight:
0.43kg

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