This highly acclaimed textbook is a worldwide bestseller, recognized for its emphasis on the mechanisms by which drugs act at the cellular and molecular levels and how that relates to their overall pharmacological effects and clinical uses. The 5th Edition includes four new chapters, a reorganized and expanded section on treatments for infections and cancer, and thorough updates throughout that explore new treatments and advances in molecular biology that may lead to future therapeutic options for cancer, HIV infection, osteoporosis, neurodegenerative disorders, erectile dysfunction, obesity, diabetes, atherosclerosis, cardiac failure, and more. User-friendly features include new chapter overviews ? reviews of relevant physiology and biochemistry ? boxed key points and clinical uses ? references and reading lists ? a new full-color art program ? and new "small print" sections that separate the more complex material from the main discussion thread in each chapter, leaving the depth of coverage to the reader's discretion.

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