Advances in Chemical Proteomics provides essential concepts and recent applications in the field of chemical proteomics, including chemical probes and tool compounds. The book begins with a section on probes, tool compounds and concepts for chemical proteomics, then moves on to cover applications including solid-phase reagents, fragment screening, designer compounds and protein lipidation. The second volume in the Developments in Organic Chemistry series, each chapter is written by an expert practitioner in the field. This book is a valuable reference for organic chemists and chemical biologists who are interested in developing tool compounds and reagents to measure and interrogate the proteome, develop drug leads and measure off-target effects and drug toxicity, as well as analytical chemists who are interested in better understanding organic chemistry behind commonly used reagents for quantitative proteomics and tools compounds in the emerging field of chemical proteomics.