This book presents state-of-the-art research on artificial intelligence and blockchain for future cybersecurity applications. The accepted book chapters covered many themes, including artificial intelligence and blockchain challenges, models and applications, cyber threats and intrusions analysis and detection, and many other applications for smart cyber ecosystems. It aspires to provide a relevant reference for students, researchers, engineers, and professionals working in this particular area or those interested in grasping its diverse facets and exploring the latest advances on artificial intelligence and blockchain for future cybersecurity applications.