This text offers educators practical application of brain research through the Brain-Targeted Teaching Model - an instructional framework that uses brain research to guide teachers in planning, implementing and evaluating instruction. This model will increase the potential of brain research to inform instructional strategies and to suggest ways to organize schools or design curriculum on a school-wide or district-wide basis. Featured topics include: a description of brain anatomy; brain research findings; suggestions to provide a supportive yet challenging emotional climate for learning; the important role the physical environment plays in learning; ideas for enhancing instruction through organized and attractive classroom space; and stages of planning and implementing a learning unit.