This volume contains the proceedings of DAIS 2008, the 8th IFIP International Conference on Distributed Applications and Interoperable Systems. The conf- ence was held in Oslo, Norway during June 4-6, 2008 as part of the DisCoTec (Distributed Object Techniques) federated conference, in conjunction with the 10th International Conference on Coordination Models and Languages (COOR- DINATION) and the 10th IFIP International Conference on Formal Methods for Open Object-Based Distributed Systems (FMOODS). The conference was sponsored by IFIP (International Federation for Information Processing) and was organized by the IFIP Working Group 6.1. Distributed applications and interoperable systems have become an integral part of everyday living and hence part of the socio-economic ecosystem of our humanenvironment.Withsuchpervasivedistributionofsoftwaresystemsacross a multitude of heterogeneous environments and user domains, distributed app- cations must support seamless provision of services, as well as service evolution and adaptability to ensure long-term sustainability. This support must go - yond the provision of individual services in isolation, towards systems in which such services can interoperate and be integrated into the everyday environment catering for the changing needs of their users.