Years of filming, extreme dangers, and daring rescues have taken their toll on documentary producer Pero Baltazar and his team. To relax and reconnect with the East African wildlife they love, Pero organizes a walking safari for him, his camerawoman Nancy Breiton, and their elite guide Mbuno Waliangulu. Still, Pero has trouble truly disconnecting from work. When the team comes across a herd of elephants making their annual migration north of Lake Rudolf, Pero decides the team will film their journey from Kenya into Ethiopia along the Omo River.

What begins as a peaceful trip quickly turns into a chaotic nightmare as the trio crosses paths with a crew of poachers whose ivory sales are financing terrorists. The three are determined to protect the endangered herd from slaughter, and Mbuno enlists the help of local tribesmen. But the corruption of ivory poachers has deep roots that stretch to UN refugee camps, Chinese gangs, and the Iranian elite Islamic Revolutionary Guard. Faced with overwhelming odds, the trio must now rely on Pero's contacts in the CIA, as well as Mbuno's skills in the bush, if they hope to ever return from this excursion alive . . .