This book constitutes the refereed proceedings of the 10th International Conference on Parallel Computing, Euro-Par 2004, held in Pisa, Italy in August/September 2004. The 122 revised papers presented together with 3 invited papers were carefully reviewed and selected from 352 submissions. The papers are organized in topical sections on support tools and environments, performance evaluation, scheduling and load balancing, compilers and high performance, parallel and distributed databases, grid and cluster computing, applications on high performance clusters, parallel computer architecture and ILP, distributed systems and algorithms, parallel programming, numerical algorithms, high performance multimedia, theory and algorithms for parallel computing, routing and communication in interconnection networks, mobile computing, integrated problem solving environments, high performance bioinformatics, and peer-to-peer and Web computing.