Dr. Kay Scarpetta, chief medical examiner of Virginia and consultant for the FBI, is in the midst of a late-night autopsy at the morgue when the call comes: Gault, the sadistic psychopath who has eluded capture for years, has struck again.

She and longtime FBI and police colleagues Benton Wesley and Captain Pete Marino fly to the eerie early-morning scene, where they immediately recognize Gault's grizzly handiwork. But no one seems to know his bald female victim, whose naked body has been propped up against a frozen fountain. It makes no sense that she apparently disrobed in the bitter cold without a struggle and walked barefoot over snow to her death.

While Scarpetta sorts through the strange forensic evidence, Gault kills again. But the prey he ultimately seeks is Scarpetta, for it becomes increasingly apparent that he is as focused on her as she is on him. It may be possible that he kills to impress her, and that he's trying to get at her through her young niece, Lucy, who is the brains behind CAIN, the worldwide FBI computer network.

Through what proves to be Scarpetta's most frightening chase, she can almost sense the evil, electric presence of her nemesis. But when she draws close, he slips back into the darkness, waiting for the time when they at last meet. . . .