Free Shipping on Order Over $60
AfterPay Available
Gap Junctions in the Nervous System

Gap Junctions in the Nervous System

by David C. Spray and Rolf Dermietzel
Publication Date: 13/11/2013
or 4 easy payments of $53.31 with
This item qualifies for FREE delivery
A Cytoplasm Connexon or Hemichannel Cytoplasm external loop I - P. M. N-Termlnus Fig. 1. 1. Topology of gap junction channels. (A) Cap junction channels, extending from the cytoplasm of one cell to the cytoplasm of another, are formed by two connexons or hemichannels connected across extracellular space. (B) Each connexon is formed from six connexin subunits, each having four membrane-spanning domains and both amino and carboxyl termini within the cytoplasm. External/oops (I and II} are believed to provide the high affinity interactions between the hemichannels. 4 Gap }unctions in the Nervous System P-region of voltage sensitive nonjunctional molecules; these contributed disulfide 9 channels. And Delmar's group has ob- bridges are presumably involved in intra- tained evidence that intracellular acidifi- connexin and inter-EL loop tertiary struc- cation may result in a conformational ture.
An old observation that should be change analogous to the ball and chain repeated stoichiometrically with modern techniques is that gap junction channels model of inactivation of voltage gated ionic can be split into connexons or hemi- channels, whereby the carboxyl terminal channels using hyperosmotic disaccharide portion of connexin43 binds to CL, closing 23 solutions again implying that linkage is the channel. Higher order structure of the channel not covalent. is believed to consist of six connexins form- ing the hemichannel or connexon in a 3.
Publication Date:
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Country of origin:
Dimensions (mm):

This title is in stock with our Australian supplier and arrives at our Sydney warehouse within 10-15 working days of you placing an order.

Once received into our warehouse we will despatch it to you with a Shipping Notification which includes online tracking.

Please check the estimated delivery times below for your region, for after your order is despatched from our warehouse:

ACT Metro  2 working days

NSW Metro  2 working days

NSW Rural  2 - 3 working days

NSW Remote  2 - 5 working days

NT Metro  3 - 6 working days

NT Remote  4 - 10 working days

QLD Metro  2 - 4 working days

QLD Rural  2 - 5 working days

QLD Remote  2 - 7 working days

SA Metro  2 - 5 working days

SA Rural  3 - 6 working days

SA Remote  3 - 7 working days

TAS Metro  3 - 6 working days

TAS Rural  3 - 6 working days

VIC Metro  2 - 3 working days

VIC Rural  2 - 4 working days

VIC Remote  2 - 5 working days

WA Metro  3 - 6 working days

WA Rural  4 - 8 working days

WA Remote  4 - 12 working days

Customer Reviews

Be the first to review Gap Junctions in the Nervous System.