Kidney disease and dialysis have been at the center of some of the most important social developments in American medicine: the birth of bioethics and the passage of the only "Medicare for All" bill that made dialysis treatment free for the thousands of Americans who need it. Yet they also provide stark examples of where American medicine has gone horribly wrong: in prioritizing profits over patients and in promulgating an ever-wider class and race divide in quality of care. The preponderance of dialysis centers in poor neighborhoods is stark evidence of something gone seriously awry. Tom Mueller's story of the wonder and corruption of dialysis stars groundbreaking scientists, heroic patients, doctors, and whistleblowers who fight for more humane and effective treatments-alongside those who advocate, sometimes colorfully, for maximizing profits. How To Make a Killing asks: What would it take to bring American medicine and society back to good health?