Yuji Itadori is resolved to save the world from cursed demons, but he soon learns that the best way to do it is to slowly lose his humanity and become one himself!

In a world where cursed spirits feed on unsuspecting humans, fragments of the legendary and feared demon Ryomen Sukuna were lost and scattered about. Should any demon consume Sukuna's body parts, the power they gain could destroy the world as we know it. Fortunately, there exists a mysterious school of Jujutsu Sorcerers who exist to protect the precarious existence of the living from the supernatural!

While investigating a strange set of mysterious deaths, Itadori meets Junpei, a troubled kid who is often bullied at school. However, Junpei is also befriended by the culprit behind the bloody incident-Mahito, a mischievous cursed spirit! Mahito sets in motion a devious plan involving Junpei, hoping to ensnare Itadori as well.