decades and provided insights into psychobiological, behavioral, and genetic factors that contribute to the onset and maintenance of substance use disorders and associated neuropsychological abnormalities. This
research has provided a strong empirical foundation that has direct implications for clinical neuropsychological practice and created a need to provide the practitioner with a cogent and up-to-date summary of current developments, which is the goal of this volume. Chapters in this volume are organized into three sections that are designed to provide a translational overview of basic research and treatment findings regarding addictions, neuropsychological and neurological sequalae of the most
common substances of abuse, and consideration of special issues that might confound interpretation of neuropsychological test results. Section I provides an overview of addictions, including diagnoses
based on the DSM-IV, as well as the most current conceptualizations of addiction from psychobiological, genetic, and behavioral and no economics perspectives, providing the reader with a broad evidence-based conceptual framework. Section II reviews the most common substances of abuse including coverage of structural and functional neuroimaging findings, epidemiological evidence, and neuropsychological sequelae. Substances included in this section represent the most commonly encountered drugs of
abuse. Section III includes coverage of the number of special topics, including specific issues related to psychiatric, medical, and neurological comorbidities. Topics included in this section
represent areas of common concerns faced by clinical neuropsychologists in the interpretation and application of neuropsychological test results.