Ana's average, suburban life is turned upside down when she's offered a place at the exclusive boarding school in New Mexico that both of her late parents attended. As she struggles to navigate the wealthy cliques of her new school, mysterious things begin to occur: sudden power failures, terrible storms, and even an earthquake!

Ana soon learns that she and three other girls--with Chinese, Navajo, and Egyptian heritages--harbor connections to priceless objects in the school's museum, and the museum's curator, Ms. Benitez, is adamant that the girls understand their ancestry, and it's importance.

It turns out that the school sits on top of a mysterious temple, the ancient meeting place of the dangerous Brotherhood of Chaos. And when one of the priceless museum objects is shattered, the girls find out exactly why their heritage is so important: they have the power to turn into wildcats! Now in their powerful forms of jaguar, tiger, puma, and lion they must work together to fight the chaos spirits unleashed in the ensuing battle...and uncover the terrifying plans of those who want to resurrect the Brotherhood of Chaos.