Set in a retro-future populated by canines, Dogs of Mars follows the travails of Sasuke Hattori and his crew of prototype super-soldiers, known as the X-dogs. Created by Mars to defend her during the war with Earth, the X-dogs face a new threat in this peaceful age; a rampant alien bio-weapon dubbed simply 'the Mold'. Armed with Sasuke's latest invention, the RIG, the X-dogs must not only navigate Mold-infected space stations, but also the demands and foibles of a society that shuns them.