When a New York subway station is torn apart by inconceivably powerful forces, Richard Wentworth--feared by the Underworld as The Spider--springs into action. Prowling by night to intercept the next attack, Wentworth encounters a band of destroyers far different than any who ever challenged him before--a fearless, merciless foe that does not quail before The Spider's menacing laugh and which sheds his avenging bullets without injury. As a reign of sabotage sweeps the nation, the Master of Men realizes that an old enemy has returned from the grave. But which one? There is only a cryptic warning symbol signed with the cruel taunt, "I AM BACK." While The Spider deploys new weapons to combat this horrific challenge, the F.B.I. sends its top man-hunters into the fray, a trio of disgraced agents whose orders are to blast The Spider on sight. Caught between bulletproof Steel Men and Federal guns, The Spider struggles to balk the destruction of Manhattan while facing a personal holocaust....with his unknown enemy determined to permanently brand Richard Wentworth with his own searing symbol of guilt-the seal of The Spider! Guest starring the F.B.I.'s infamous Suicide Squad!