This book delves into the multifaceted world of sleep apnea, presenting the latest advancements, challenges, and perspectives in the field. The book covers various topics, including neuro-stimulator use, positive airway pressure therapies, non-PAP and non-surgical treatments, surgical interventions, diagnosis and management of various sleep apnea phenotypes and comorbidities, and special populations such as pediatric and intensive care unit patients. The book discusses the pathophysiology and mechanisms underlying sleep apnea, examining the role of circulating miRNA as a potential biomarker for diagnosis. It also addresses the adverse health consequences associated with sleep apnea, including cardiovascular disease, diabetes, cancer, and hypertension. Furthermore, the book explores the application of telemedicine and wearable technologies in diagnosing and treating sleep apnea, as well as the impact of external factors such as the COVID-19 pandemic and traffic safety concerns related to sleep deprivation and sleep disorders. The book also highlights the importance of perioperative assessment and management of patients with sleep disorders, the role of REM sleep in sleep disorders, recent advances in sleep during pregnancy and postpartum, and the influence of sleep disturbances on hospitalized and intensive care unit patients. With contributions from experts in the field, this book offers valuable insights into the current state of sleep apnea research and practice, serving as a solid foundation for healthcare professionals, researchers, and students interested in understanding and addressing this prevalent sleep disorder. By providing a comprehensive overview of the field, this book aims to inspire further research and innovation in the diagnosis, treatment, and management of sleep apnea and related sleep disorders.