Part I: Attachment of Dissimilar Materials: Challenges and Solutions.- The Challenge of Attaching Dissimilar Materials.- Functionally Graded Materials in Engineering.- Singularities at the Attachment of Dissimilar Materials.- Part II: Natural Examples of Transitions from Stiff to Compliant Materials.- Ligament and Tendon Enthesis: Anatomy and Mechanics.- The Bone-Cartilage Interface.- Muscle-Tendon Interactions in The Absence of Bones: Lessons from the Fruit Fly, Drosophilf.- Dentin/Adhesive Interfaces in Teeth.- Specific Adhesion of Soft Elastic Materials.- Diversified Material Designs in The Biological Underwater Adhesives.- Mechanics of Self-Similar Hierarchical Adhesive Structures Inspired by Gecko.- Part III: Regeneration of Interfaces - Development, Healing, and Tissue Engineering.- Mechanobiology at The Attachment of Tendon to Bone.- Soft Tissue to Bone Healing in Rotator Cuff Repair.- Soft Tissue to Bone Healing in Anterior Cruciate Ligament Reconstruction.- Engineering Graded Tissue Interfaces.- Engineering Fibrous Tissues and their Interface with Bone.- Synthesis of Layered, Graded Bioscaffolds.