Told through a series of quirky, irreverent short stories and letters home during the early 1980s, The Deaf Heart chronicles a year in the life of Dempsey "Max" McCall, a Deaf biomedical photography resident at a teaching hospital on the island of Galveston, Texas. Max strives to become certified as a Registered Biological Photographer while straddling the deaf and hearing worlds. He befriends Reynaldo, an impoverished Deaf Mexican, and they go on a number of unusual escapades around the island.

At the hospital, Max has to contend with hearing doctors, nurses, scientists, and teachers. While struggling through the rigors of his residency and running into bad luck in meeting women, Max discovers an ally in his hearing housemate Zag, a fellow resident who is also vying for certification. Toward the end of his residency, Max meets Maddy, a Deaf woman who helps bring balance to his life.
Author Willy Conley's stories, some humorous, some poignant, reveal Max's struggles and triumphs as he attempts to succeed in the hearing world while at the same time navigating the multicultural and linguistic diversity within the Deaf world.