This proceedings volume addresses advances in global optimization—a multidisciplinary research field that deals with the analysis, characterization and computation of global minima and/or maxima of nonlinear, non-convex and nonsmooth functions in continuous or discrete forms. The volume contains selected papers from the third biannual World Congress on Global Optimization in Engineering & Science (WCGO), held in the Yellow Mountains, Anhui, China on July 8-12, 2013. The papers fall into eight topical sections: mathematical programming; combinatorial optimization; duality theory; topology optimization; variational inequalities and complementarity problems; numerical optimization; stochastic models and simulation and complex simulation and supply chain analysis.