This book features high-quality, peer-reviewed papers from the 28th International Conference Systems Engineering (ICSEng 2021), held at Wrcław University of Science and Technology, Wrocław, Poland, on December 14–16, 2021. Presenting the latest developments and technical solutions in systems engineering, it covers a variety of topics, such as analog and digital hardware systems, artificial intelligence and machine learning, distance learning & games, E-business systems, financial technology, general control systems, hyper-automation and Industry 4.0, Internet of things, sensor and biometric systems, medical systems and applications, robotics, computer vision, HCI, and parallel and distributed systems. As such, it helps those in the computer industry and academia to use the advances in next-generation systems engineering technology to shape real-world applications.