This book explores the transformative effects of AI and ML on software engineering. It emphasizes the potential of cutting-edge software development technologies such as Generative AI and ML applications. This book incorporates data-driven strategies across the entire software development life cycle, from requirements elicitation and design to coding, testing, and deployment. It illustrates the evolution from traditional frameworks to agile and DevOps methodologies. The potential of Generative AI for automating repetitive tasks and enhancing code quality is highlighted, along with ML applications in optimizing testing, effort estimation, design pattern recognition, fault prediction, debugging, and security through anomaly detection. These techniques have significantly improved software development efficiency, predictability, and project management effectiveness. While remarkable progress has been made, much remains to be done in this evolving area. This edited book is a timely effort toward advancing the field and promoting interdisciplinary collaboration in addressing ethical, security, and technical challenges.