This book constitutes the proceedings of the 14th International Workshop on Clinical Image-Based Procedures, CLIP 2025, held in conjunction with the 28th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2025, held in Daejeon, South Korea, on September 23, 2025.

The 11 full papers included in this book were carefully reviewed and selected from 17 submissions. The workshop focuses on translational research and provides a forum for scientific work applied to clinical practice.