This book presents the proceedings of The EAI International Conference on Computer Science: Applications in Engineering and Health Services (COMPSE 2019). The conference highlighted the latest research innovations and applications of algorithms designed for optimization applications within the fields of Science, Computer Science, Engineering, Information Technology, Management, Finance and Economics and Health Systems. Focusing on a variety of methods and systems as well as practical examples, this conference is a significant resource for post graduate-level students, decision makers, and researchers in both public and private sectors who are seeking research-based methods for modelling uncertain and unpredictable real-world problems.