Incorporating more than 20 years of the editors' and contributors' statistical work in mixed membership modeling, this handbook shows how to use these flexible modeling tools to uncover hidden patterns in modern high-dimensional multivariate data. It explores the use of the models in various application settings, including survey data, population genetics, text analysis, image processing and annotation, and molecular biology. Through examples using real data sets, readers will discover how to characterize complex multivariate data in a range of areas.