This book constitutes the refereed proceedings of the 5th International Workshop on Stroke Imaging and Treatment , SWITCH 2025, held in conjunction with MICCAI 2025, in Daejeon, South Korea, on September 23, 2025.

The 9 revised full papers presented in this volume were selected form 11 submissions. These papers highlight recent advances in image analysis for the diagnosis and intervention of ischemic and haemorrhagic stroke, with a focus on integrating artificial intelligence and computational techniques to address clinically relevant challenges.