This book constitutes the refereed conference proceedings of the 10th North American Conference - Computer Science Tracks, IEOM-CS 2025, held in Orlando, USA during June 17–19, 2025.

The 22 full papers included in this book were carefully reviewed and selected from 121 submissions. They are categorized into the following topical sections:

1. Artificial Intelligence


2. Autonomous Systems


3. Data Analysis


4. Decision Systems


5. Learning Management Systems


6. Machine Learning


7. Security Systems