This book presents the latest research perspectives on how the Industry 4.0 paradigm is challenging the process of technological and structural change and how the diversification of the economy affects structural transformation. It also explores the impact of fast-growing technologies on the transformation of socioeconomic and environmental systems, and asks whether structural and technological change can generate sustainable economic growth and employment. Further, the book presents the basic innovations (new technologies, materials, energy, etc) and industrial policies that can lead to such a structural change.