The birth of bacterial genomics since the mid-1990s brought withit several conceptual modifications and wholly new controversies. Working beyond the scope of the neo-Darwinian evolutionary synthesis, a group of leading microbial evolutionists addresses the following and related issues, often with markedly varied viewpoints: · Did the eukaryotic nucleus, cytoskeleton and cilia also orginate from symbiosis? · Do the current scenarios about he origin of mitochondria and plastids require revision? · What is the extent of lateral gene transfer (between "species") among bacteria? · Does the rDNA phylogenetic tree still stand in the age of genomics? · Is the course of the first 3 billion years of evolution even knowable?