Neurological Complications of Systematic Cancer and Antineoplastic Therapy provides an in-depth review of common manifestations related to neurology that occur in patients with systemic cancer. These include brain metastases, spinal cord compression, cerebrovascular events, and leptomeningeal disease. The book also discusses less common complications such as paraneoplastic disorders and neoplastic plexopathy.

Highlights include:

• The pathophysiology and molecular biology of cancer and the metastatic phenotype






• Metastatic spread to cranial and peripheral nerves and brachial and lumbosacral plexuses






• Metabolic and nutritional disorders






• CNS infections






• Neurological complications of immunotherapy and bone marrow transplants

Additional chapters review problems related to each specific tumor type, such as breast, lung, and colorectal, as well as gynecological cancer, genitourinary cancer, and malignant melanoma. The book also discusses neurological complications related to treatments such as radiation and chemotherapy.

Bringing clinical trial knowledge from the bench to the bedside, this volume is an essential reference for the practicing oncologist and neurologist.