At twenty-two, Chicagoan Nadine Kenney is thrilled to meet her future husband, Jamie, while vacationing in Florida. After a whirlwind, long-distance romance, Nadine leaves her friends, family, and city to join Jamie in suburban Massachusetts. Once married, they begin trying for a baby without knowing how hard that road will become.

Nadine soon faces the little-known horrors of IVF when a procedure causes severe internal bleeding, and she wakes up from emergency surgery with a six-inch scar instead of a baby bump. In the difficult year that follows, anxiety and additional failed fertility treatments threaten her new marriage and her mental state. By some saving grace, she eventually becomes pregnant naturally, but the horrors are not over: her son is diagnosed with potentially terminal kidney complications. Ultimately, Nadine learns that in an unpredictable life, the only thing she can be sure of is the healing power of hope.